
Tom Metz is a PhD-student in the group of Willeke van Roon-Mom. He did his bachelor in Biology and masters in Clinical and Molecular Neurobiology both at the University of Groningen. During his study, Tom got interested in neurodegenerative disorders and the interaction that glia and vascular cells have with neurons in the development of these diseases. Currently, he is, as a part of his PhD, working on finding out which of those cell types are involved in a rare hereditary brain disease called Dutch type cerebral amyloid angiopathy (D-CAA) using single cell RNA sequencing. The other part of his PhD focusses on finding a therapy for D-CAA. He is testing an exon skipping approach for D-CAA using antisense oligonucleotides (AONs) in a transgene mouse model.